English Name: metoclopramide
Molecular formula: C14H22ClN3O2
Molecular weight: 299.81
Chinese Name: metoclopramide; metoclopramide; metoclopramide; metoclopramide; 4- amino -5- chloro -N-[(2- B two amino) ethyl]-2- methoxy phenyl amide
Melting point: 147 ~ 151 DEG C
Properties: white to pale yellow crystalline powder, odorless, bitter taste.
Solubility: soluble in water and ethanol, insoluble in benzene, ethyl ether, slightly soluble in acetone.
Use: a powerful central antiemetic effect, for malignant, vomiting, belching, loss of appetite, indigestion and so.
Preparation or source: by Para water hydrochloric acid by esterification, acetylation, methylation of amino to acetyl - O - methoxy benzoic acid methyl ester, followed by chlorination, amination, hydrolysis.
Note: to heat, light, alkali labile, changeful color, more stable in acidic solution.